Bioinformatics software group discounts
MCBI negotiates state-wide contracts for bioinformatics programs. The resulting group software discounts allow more researchers in our academic and biotech sectors access to bioinformatics tools. MCBI also evaluates packages, hosts statewide demonstrations, and facilitates distribution of bioinformatics tools and education in their use. MCBI is currently working with microarray analysis packages, proprietary database packages, and enterprise software packages that encompass genomics & gene expression, proteomics, high-throughput screening, toxicology, etc.

Bioinformatics Software Trials
With a particularly popular and needed package, MCBI may host a trial period during which researchers may try the package at nominal cost. Trials are posted on the MCBI website. A trial of gene-expression packages that analyze microarray chips is currently underway. Software trials are used to help introduce the newest bioinformatics tools to Michigan researchers.

Biological Information Databases
MCBI provides resources to Michigan researchers for the construction of new databases for biological information, including server space, technical support, and maintenance. Databases can be private or made public for publishing data and allowing access to Michigan researchers and others. Database information could include mircoarry data, proteomic data, pre-designed oligonucleotides, metabolic pathways, etc. Researchers and small biotechs can apply for room on MCBI’s servers to develop new types of databases in a secure environment.

Supercomputing Resources
Genomics, Proteomics and Structural Biology: Michigan investigators can apply for time and space on MCBI’s 64 node Linux cluster, for intensive bioinformatics computing. The cluster is located in Ann Arbor and run by MCBI staff at the University of Michigan. As part of this cluster, a BLAST server is available for intensive BLAST searches. A 16 node SGI system is available through the Michigan State University for structural biology applications, including analysis of X-ray and NMR structural data. Plans are in place for a Beowulf cluster to be added to this facility. Access to Pittsburgh Supercomputing facilities for molecular modeling is also available.

Bioinformatics Consulting and Algorithm Development
MCBI can aid investigators in algorithm development, or use of existing tools and public databases through our consulting program. Our scientists can contribute technical expertise for SBIR and academic grants.

Bioinformatics Middleware and Networking
MCBI has an ongoing development program to connect researchers across the state, allowing sharing of bioinformatics data and resources. This project addresses throughput, compatibility, and security issues in different bioinformatics realms. Researchers can contact MCBI for information on this statewide program.

Portal to Michigan Bioinformatics Projects
MCBI is developing a web-based portal to link researchers to Bioinformatics projects, including software packages and databases created by Michigan researchers.

Bioinformatics Education Portal
Many of our educational institutions across Michigan have newly developed Bioinformatics classes, and are developing full programs. In 2002, MCBI will create a Web-based portal to the Bioinformatics educational opportunities in Michigan.

Usergroups
As part of its Web-Site, MCBI is launching Web-based threaded discussion groups for our Michigan bioinformatics users.